|
KMID : 1098420050130060245
|
|
Korean Journal of Medicinal Crop Science
2005 Volume.13 No. 6 p.245 ~ p.249
|
|
|
Anti-inflammatory Activity of the Ethanol Extract from Magnoliae Flos on PAR2-mediated Edema
|
|
Lim Jong-Pil
Park Yeong-Seo
|
|
|
Abstract
|
|
|
|
The flower of Magnolia denudata Desrousseaux(Magnoliaceae) has long been used for treatment of nasal disorder in Korea. The physiological activity of the Magnoliae Flos ethanol extract (MFX) was investigated. MFX showed antimicrobial activity. At doses of 100 and 200 mg/kg, MFX showed significant inhibition on both change in paw volume and vascular permeability. MFX (100 mg/kg) significantly inhibited PAR2 agonist-induced myeloperoxidase (MPO) activity in paw tissue. These results indicate that MFX has anti-inflammatory activity in PAR2-mediated paw edema.
|
|
|
KEYWORD
|
|
|
Magnoliae Flos, Anti-inflammatory, Trypsin, tc-NH_2, Paw edema
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|